{"id":52,"date":"2017-12-01T19:04:52","date_gmt":"2017-12-01T11:04:52","guid":{"rendered":"http:\/\/u2.cfoh.org.tw\/?page_id=52"},"modified":"2024-11-25T14:52:43","modified_gmt":"2024-11-25T06:52:43","slug":"mma","status":"publish","type":"page","link":"https:\/\/www.cfoh.org.tw\/index.php\/item\/mma\/","title":{"rendered":"\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7 (MMA)"},"content":{"rendered":"<div class=\"artical\">\n<h3 style=\"text-align: justify;\"><strong><span style=\"font-size: 14pt;\">\u4f55\u8b02\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7?<\/span><\/strong><\/h3>\n<p style=\"text-align: justify; padding-left: 40px;\">\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7\u662f\u9ad4\u67d3\u8272\u9ad4\u96b1\u6027\u907a\u50b3\u7684\u75be\u75c5\u3002\u5b83\u662f\u56e0\u70ba\u7532\u57fa\u4e19\u4e8c\u9178\u8f14\u9176A\u8b8a\u4f4d\u9176\uff08methylmalonyl- CoA mutase\uff09\u529f\u80fd\u7570\u5e38\u6216\u94b4\u80fa\u7d20(Cobalamin)\u4ee3\u8b1d\u7570\u5e38\uff0c\u5c0e\u81f4\u9ad4\u5167\u7532\u57fa\u4e19\u4e8c\u9178\u3001\u4e19\u9178\u7b49\u6709\u6a5f\u9178\u84c4\u7a4d\uff0c\u9020\u6210\u795e\u7d93\u7cfb\u7d71\u640d\u5bb3\uff0c\u56b4\u91cd\u6642\u5f15\u8d77\u916e\u75c7\u9178\u4e2d\u6bd2\u3001\u4f4e\u8840\u7cd6\u3001\u9ad8\u8840\u6c28\u3001\u9ad8\u7518\u80fa\u9178\u8840\u75c7\uff0c\u65b0\u751f\u5152\u3001\u5b30\u5e7c\u5152\u671f\u6b7b\u4ea1\u7387\u5f88\u9ad8\u3002<\/p>\n<\/div>\n<div class=\"artical\" style=\"text-align: justify;\">\n<h3><strong><span style=\"font-size: 14pt;\">\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7\u4e4b\u75c7\u72c0?<\/span><\/strong><\/h3>\n<p style=\"padding-left: 40px;\">\u7532\u57fa\u4e19\u4e8c\u9178\u8f14\u9176A\u8b8a\u4f4d\u9176\uff08methylmalonyl- CoA mutase\uff09\u529f\u80fd\u7570\u5e38\uff0c\u75c5\u60a3\u75c7\u72c0\u8f03\u56b4\u91cd\uff0c\u901a\u5e38\u5728\u65b0\u751f\u5152\u671f\u767c\u75c5\uff0c\u6703\u6709\u5614\u5410\u3001\u812b\u6c34\u3001\u53ad\u98df\u3001\u547c\u5438\u6025\u4fc3\u7b49\u75c7\u72c0\u751a\u81f3\u660f\u8ff7\u3001\u6b7b\u4ea1\u3002\u94b4\u80fa\u7d20(Cobalamin)\u4ee3\u8b1d\u7570\u5e38\uff0c\u591a\u534a\u5448\u73fe\u9ad4\u91cd\u4e0d\u589e\u52a0\uff0c\u5614\u5410\u53ca\u5fc3\u667a\u767c\u80b2\u9072\u7de9\u7b49\u8f03\u8f15\u5fae\u7684\u75c7\u72c0\uff0c\u767c\u75c5\u4e5f\u8f03\u665a\u3002<\/p>\n<\/div>\n<div class=\"artical\" style=\"text-align: justify;\">\n<h3><strong><span style=\"font-size: 14pt;\">\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7\u767c\u751f\u7387\u70ba\u4f55?<\/span><\/strong><\/h3>\n<p style=\"padding-left: 40px;\">\u76ee\u524d\u570b\u5167\u767c\u751f\u7387\u4ecd\u5728\u8a55\u4f30\u4e2d\u3002\u570b\u5916\u7d71\u8a08\u76db\u884c\u7387\u7d04\u70ba\u4e94\u842c\u5206\u4e4b\u4e00\u3002<\/p>\n<\/div>\n<div class=\"artical\" style=\"text-align: justify;\">\n<h3><strong><span style=\"font-size: 14pt;\">\u65b0\u751f\u5152\u7be9\u6aa2\u901a\u77e5\u7570\u5e38(\u7591\u967d\u6027)\u4e4b\u8655\u7406?<\/span><\/strong><\/h3>\n<p style=\"padding-left: 40px;\">\u65b0\u751f\u5152\u7be9\u6aa2\u65b9\u6cd5\u662f\u6e2c\u5b9a\u6ffe\u7d19\u8840\u7247\u6aa2\u9ad4\u4e2d\u4e19\u9178\uff08C3\uff09\u7684\u542b\u91cf\uff0c\u7576\u8840\u7247\u542b\u91cf\u9ad8\u65bc\u6b63\u5e38\u503c\uff0c\u63a5\u7372\u901a\u77e5\u5f8c\u8acb\u5118\u901f\u914d\u5408\u91ab\u7642\u4eba\u54e1\u6307\u793a\u56de\u8a3a\uff0c\u5982\u5b30\u5152\u6709\u7279\u6b8a\u75c7\u72c0\u7522\u751f\u7acb\u5373\u8207\u65b0\u751f\u5152\u7be9\u6aa2\u4e2d\u5fc3\u6216\u7576\u5730\u6240\u5c6c\u8f49\u4ecb\u91ab\u9662\u806f\u7d61\uff0c\u5c0b\u6c42\u6b63\u78ba\u91ab\u7642\u652f\u63f4\u3002<\/p>\n<\/div>\n<div class=\"artical\" style=\"text-align: justify;\">\n<h3><strong><span style=\"font-size: 14pt;\">\u5982\u4f55\u8a3a\u65b7\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7?<\/span><\/strong><\/h3>\n<p style=\"padding-left: 40px;\">\u7531\u65bc\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7\u60a3\u8005\u7684\u81e8\u5e8a\u8868\u73fe\u500b\u5225\u5dee\u7570\u5f88\u5927\uff0c\u9020\u6210\u8a3a\u65b7\u56f0\u96e3\uff0c\u76ee\u524d\u662f\u4ee5\u4ee3\u8b1d\u6027\u9178\u8840\u75c7\u3001\u9ad8\u8840\u6c28\u7b49\u6578\u503c\u4f86\u6aa2\u67e5\uff0c\u53e6\u5916\u9700\u9032\u884c\u6709\u6a5f\u9178\u5206\u6790\uff0c\u4f8b\u5982\u5229\u7528\u5c3f\u6db2\u8584\u8272\u5c64\u505a\u5b9a\u6027\u5206\u6790\uff0c\u6216\u9032\u4e00\u6b65\u4ee5\u6c23\u76f8\u8272\u5c64\u5206\u6790\uff08gas chromatography\uff09\u6216\u6c23\u76f8\u8cea\u8b5c\u5206\u6790\uff08GC-mass spectrometry\uff09\u9032\u884c\u78ba\u8a3a\u6aa2\u6e2c\u5c3f\u6db2\u4e2d\u7532\u57fa\u4e19\u4e8c\u9178(Methylmalonic acid) \uff0c\u4e19\u9178(Propionic acid) \uff0c\u7532\u57fa\u6ab8\u6aac\u9178(Methylcitrate)\u4ee5\u53ca3-\u7fa5\u57fa\u4e19\u9178(3-OH propionic acid)\u4e4b\u542b\u91cf\uff0c\u53e6\u6e2c\u5b9a\u6dcb\u5df4\u7d30\u80de\u4e2d\u7532\u57fa\u4e19\u4e8c\u9178\u8f14\u9176A\u8b8a\u4f4d\u9176\uff08methylmalonyl- CoA mutase\uff09\u4e4b\u6d3b\u6027\u3002<\/p>\n<\/div>\n<div class=\"artical\">\n<h3 style=\"text-align: justify;\"><strong><span style=\"font-size: 14pt;\">\u5982\u4f55\u6cbb\u7642\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7?<\/span><\/strong><\/h3>\n<p style=\"text-align: justify; padding-left: 40px;\">\u5c0d\u65bcVitB12\u6709\u6548\u578b\u7684\u75c5\u60a3\uff0c\u9808\u7d66\u4e88\u7dad\u751f\u7d20B12\uff08\u6bcf\u65e51\u81f32 mg Cyanocobalamin\u6216hydroxycobalamin\uff09\u6cbb\u7642\uff0c\u9577\u671f\u7dad\u6301\u5291\u91cf\u70ba\u6bcf\u9031\u808c\u6ce81 mg\u4e00\u6b21\u6216\u6bcf\u5929\u53e3\u670d10~20 mg\u3002\u5c0d\u65bcVitB12\u7121\u6548\u578b\u7684\u91cd\u75c7\u60a3\u8005\u9084\u9700\u7d66\u4e88\u4f4e\u86cb\u767d(\u9650\u5236methionine, threonine, valine, isoleucine\u80fa\u57fa\u9178\u4e4b\u7279\u6b8a\u914d\u65b9\u5976\u7c89)\u3001\u9ad8\u71b1\u91cf\u98f2\u98df\u63a7\u5236\uff0c\u4f7f\u8840\u6db2\u3001\u5c3f\u6db2\u4e2d\u7684\u7532\u57fa\u4e19\u4e8c\u9178\u6fc3\u5ea6\u7dad\u6301\u5728\u7406\u60f3\u7bc4\u570d\u3002\u6025\u6027\u9178\u4e2d\u6bd2\u767c\u4f5c\u6642\u61c9\u4ee5\u88dc\u5145\u6db2\u9ad4\u3001\u907f\u514d\u9178\u4e2d\u6bd2\u70ba\u4e3b\u3002<\/p>\n<h3><strong><span style=\"font-size: 14pt;\">\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7\u7684\u7be9\u6aa2\u65b9\u6cd5<\/span><\/strong><\/h3>\n<ul>\n<li style=\"text-align: justify;\">\u7b2c\u4e00\u7dda\u6aa2\u9a57\n<ul style=\"list-style-type: square;\">\n<li>\u6aa2\u9a57\u65b9\u5f0f\uff1a\u751f\u5316\u6aa2\u9a57\uff0c\u4f7f\u7528\u542b\u7a69\u5b9a\u540c\u4f4d\u7d20\u6a19\u8a18\u7684\u5167\u90e8\u6a19\u6e96\u54c1\uff08Internal Standard\uff09\u6eb6\u5291\u8403\u53d6\u4e7e\u71e5\u8840\u9ede\u4e2d\u7684\u6709\u6a5f\u9178\uff0c\u518d\u4ee5\u4e32\u806f\u8cea\u8b5c\u5100\uff08MS\/MS\uff09\u9032\u884c\u5206\u6790\u3002\uff08111.3-\u81f3\u4eca\uff09<\/li>\n<li>\u6aa2\u9a57\u8a66\u5291\uff1aNeoBase<sup>TM<\/sup>\u00a02 Non-derivatized MSMS kit\uff08PerkinElmer\uff09<\/li>\n<\/ul>\n<\/li>\n<li>\u7b2c\u4e8c\u7dda\u6aa2\u9a57\n<ul style=\"list-style-type: square;\">\n<li style=\"text-align: justify;\">\u6aa2\u9a57\u65b9\u5f0f\uff1a\u751f\u5316\u6aa2\u9a57\uff0c\u6db2\u76f8\u5c64\u6790\u4e32\u806f\u8cea\u8b5c\u5100\u6cd5\uff08LC-MS\/MS\uff09\u3002\uff08108.10-\u81f3\u4eca\uff09<\/li>\n<li style=\"text-align: justify;\">\u6aa2\u9a57\u8a66\u5291\uff1aLDTs<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4f55\u8b02\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7? \u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7\u662f\u9ad4\u67d3\u8272\u9ad4\u96b1\u6027\u907a\u50b3\u7684\u75be\u75c5\u3002\u5b83\u662f\u56e0\u70ba\u7532\u57fa\u4e19\u4e8c\u9178\u8f14\u9176A\u8b8a\u4f4d\u9176\uff08methylma &#8230; <a title=\"\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7 (MMA)\" class=\"read-more\" href=\"https:\/\/www.cfoh.org.tw\/index.php\/item\/mma\/\" aria-label=\"\u95b1\u8b80\u3008\u7532\u57fa\u4e19\u4e8c\u9178\u8840\u75c7 (MMA)\u3009\u5168\u6587\">\u95b1\u8b80\u5168\u6587<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":781,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P9uzrk-Q","_links":{"self":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/52"}],"collection":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/comments?post=52"}],"version-history":[{"count":7,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/52\/revisions"}],"predecessor-version":[{"id":2622,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/52\/revisions\/2622"}],"up":[{"embeddable":true,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/781"}],"wp:attachment":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/media?parent=52"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}