{"id":579,"date":"2019-09-03T12:55:58","date_gmt":"2019-09-03T04:55:58","guid":{"rendered":"http:\/\/u5.cfoh.org.tw\/?page_id=579"},"modified":"2024-11-25T15:05:47","modified_gmt":"2024-11-25T07:05:47","slug":"vlcadd","status":"publish","type":"page","link":"https:\/\/www.cfoh.org.tw\/index.php\/item\/vlcadd\/","title":{"rendered":"\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7 (VLCAD)"},"content":{"rendered":"\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\"><strong>\u4ec0\u9ebc\u662f\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7\uff1f<\/strong><\/span><\/p>\n<p style=\"padding-left: 40px;\">\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7\u60a3\u8005\u8eab\u9ad4\u7f3a\u4e4f\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7121\u6cd5\u5c07\u67d0\u4e9b\u8102\u80aa\uff08\u7a31\u70ba\u6975\u9577\u93c8\u8102\u80aa\u9178\uff09\u9069\u7576\u5730\u8f49\u63db\u6210\u80fd\u91cf\uff0c\u56e0\u70ba\u975e\u5e38\u9577\u93c8\u7684\u8102\u80aa\u9178\u662f\u91cd\u8981\u7684\u80fd\u91cf\u4f86\u6e90\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u5fc3\u81df\u548c\u808c\u8089\uff0c\u7f3a\u4e4f\u5f8c\u53ef\u80fd\u6703\u6709\u55dc\u7761\u548c\u4f4e\u8840\u7cd6\u7b49\u75c7\u72c0\u3002\u7576\u60a3\u8005\u9577\u6642\u9593\u7981\u98df\u3001\u75be\u75c5\u53ca\u904b\u52d5\u6642\uff0c\u6613\u8a98\u767c\u81e8\u5e8a\u75c7\u72c0\u3002<\/p>\n<p style=\"padding-left: 40px;\">\u800c\u5206\u89e3\u4e0d\u5168\u7684\u8102\u80aa\u9178\u5806\u7a4d\u5728\u7d44\u7e54\u88e1\u9020\u6210\u5fc3\u81df\u3001\u809d\u81df\u3001\u808c\u8089\u7684\u50b7\u5bb3\u3002\u9019\u6a23\u7570\u5e38\u7684\u5806\u7a4d\u6703\u5c0e\u81f4\u6b64\u75be\u75c5\u7684\u5176\u4ed6\u75c7\u72c0\uff0c\u5982\u809d\u81df\u7570\u5e38\u548c\u5371\u53ca\u751f\u547d\u7684\u5fc3\u81df\u75c5\u3002<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\"><strong>\u6975\u9577\u93c8\u91af\u8f14\u9176<\/strong><strong>A<\/strong><strong>\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7\u60a3\u8005\u75c7\u72c0<\/strong><\/span><\/p>\n<p style=\"text-align: justify; padding-left: 40px;\">VLCAD\u7f3a\u4e4f\u6709\u4e09\u7a2e\u5f62\u5f0f\uff1a\u56b4\u91cd\u65e9\u767c\u578b\u3001\u00a0\u809d\u81df\u578b\/\u4f4e\u916e\u9ad4\u6027\u4f4e\u8840\u7cd6\u578b\u548c\u665a\u767c\u6027\u808c\u8089\u75c5\u8b8a\u578b\u3002<\/p>\n<ul style=\"text-align: justify;\">\n<li><strong>\u65e9\u767c\u56b4\u91cd\u578b\uff1a<\/strong>\u5b30\u5152\u5728\u51fa\u751f\u5f8c\u5e7e\u500b\u6708\u51fa\u73fe\u5fc3\u808c\u75c5\u8b8a\u3001\u5fc3\u5305\u819c\u7a4d\u6c34\u3001\u5fc3\u5f8b\u4e0d\u6574\u3001\u808c\u5f35\u529b\u4f4e\u4e0b\u3001\u809d\u816b\u5927\u3001\u9593\u6b47\u6027\u4f4e\u8840\u7cd6\u53ca\u591a\u91cd\u5668\u5b98\u8870\u7aed\u3002\u5fc3\u81df\u75c5\u53ef\u80fd\u6703\u5371\u53ca\u751f\u547d\uff0c\u4f46\u901a\u5e38\u6703\u901a\u904e\u65e9\u671f\u6cbb\u7642\u548c\u98f2\u98df\u6539\u826f\u4f86\u6539\u5584\u3002<\/li>\n<li><strong>\u809d\u81df\u578b\/\u4f4e\u916e\u9ad4\u6027\u4f4e\u8840\u7cd6\u578b\uff1a<\/strong>\u809d\u81df\u6216\u4f4e\u8840\u7cd6\u75c7\u5f62\u5f0f\u5f71\u97ff\u7684\u4eba\u901a\u5e38\u5728\u5e7c\u5152\u51fa\u73fe\u75c7\u72c0\uff0c\u4ee5\u4f4e\u916e\u9ad4\u6027\u4f4e\u8840\u7cd6(hypoketotic hypoglycemia)\u53ca\u809d\u816b\u5927\u8868\u73fe\u3002<\/li>\n<li><strong>\u665a\u767c\u6027\u808c\u8089\u75c5\u8b8a\u578b\uff1a<\/strong>\u8f03\u665a\u767c\u75c5\uff0c\u4ee5\u9593\u6b47\u6027\u6a6b\u7d0b\u808c\u6eb6\u89e3\u75c7(rhabdomyolysis)\u3001\u808c\u8089\u75d9\u6523(muscle cramps)\u3001\u808c\u8089\u75bc\u75db\u53ca\u904b\u52d5\u4e0d\u8010\u4f86\u8868\u73fe\u3002\u662fVLCAD\u7f3a\u4e4f\u75c7\u7684\u6700\u5e38\u898b\u5f62\u5f0f\uff0c\u7576\u808c\u8089\u7d44\u7e54\u88ab\u7834\u58de\u6703\u91cb\u51fa\u7a31\u70ba\u808c\u7d05\u7d20\u7684\u86cb\u767d\uff0c\u5176\u7d93\u904e\u814e\u81df\u9032\u5230\u5c3f\u6db2\u4e2d\u6703\u4f7f\u5c3f\u6db2\u8b8a\u6210\u7d05\u8272\u6216\u8910\u8272\u3002<\/li>\n<\/ul>\n<p style=\"text-align: justify; padding-left: 40px;\">\u5728\u65e9\u767c\u56b4\u91cd\u578b\u548c\u809d\u81df\u578b\/\u4f4e\u916e\u9ad4\u6027\u4f4e\u8840\u7cd6\u578b\u4e2d\u89c0\u5bdf\u5230\u7684\u4f4e\u8840\u7cd6\u767c\u4f5c\u53ef\u5c0e\u81f4\u5152\u7ae5\u611f\u89ba\u8106\u5f31\uff0c\u6416\u6643\u548c\/\u6216\u982d\u6688\u6fd5\u51b7\u7684\u76ae\u819a\u3002\u5982\u679c\u4e0d\u6cbb\u7642\uff0c\u53ef\u80fd\u5c0e\u81f4\u660f\u8ff7\uff0c\u751a\u81f3\u6b7b\u4ea1\u3002<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\"><strong>\u767c\u751f\u7387\u53ca\u907a\u50b3\u6a21\u5f0f<\/strong><\/span><\/p>\n<p style=\"text-align: justify; padding-left: 40px;\">\u76ee\u524d\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7\u5df2\u5217\u70ba\u6211\u570b\u516c\u544a\u7f55\u898b\u75be\u75c5\uff0c\u76ee\u524d\u570b\u5167\u767c\u751f\u7387\u7d0453\u842c\u5206\u4e4b\u4e00(\u90e8\u5206\u8cc7\u6599\u986f\u793a\u53f0\u7063\u5730\u5340\u76db\u884c\u7387\u9810\u4f30\u7d04\u56db\u842c\u81f3\u5341\u4e8c\u842c\u4eba\u4e2d\u6703\u6709\u4e00\u4eba\u7f79\u60a3\u6b64\u75c7)\u3002<\/p>\n<p style=\"text-align: justify; padding-left: 40px;\">\u6b64\u75be\u75c5\u907a\u50b3\u6a21\u5f0f\u70ba\u9ad4\u67d3\u8272\u9ad4\u96b1\u6027\u907a\u50b3\uff0c<em>ACADVL<\/em>\u57fa\u56e0\u4f4d\u65bc\u7b2c17\u865f\u67d3\u8272\u9ad4\u7684\u77ed\u81c2(17p13 .1)\u4e0a\u3002<em>ACADVL<\/em>\u57fa\u56e0\u63a7\u5236\u6975\u9577\u93c8\u91af\u8f14\u9176A\u53bb\u6c2b\u9176\u7684\u5408\u6210\uff0c\u7576<em>ACADVL<\/em>\u57fa\u56e0\u7f3a\u9677\u9020\u6210\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20(VLCAD)\u7f3a\u4e4f\u3002<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\"><strong>\u65b0\u751f\u5152\u7be9\u6aa2\u7591\u967d\u6027\u4e4b\u8655\u7406<\/strong><\/span><\/p>\n<p style=\"text-align: justify; padding-left: 40px;\">\u65b0\u751f\u5152\u7be9\u6aa2\u65b9\u6cd5\u70ba\u5229\u7528\u4e32\u806f\u8cea\u8b5c\u5100\u6e2c\u91cf\u9ad4\u5167\u6975\u9577\u93c8\u8102\u80aa\u9178\u4e4b\u6fc3\u5ea6(C14:1\u3001C14)\u3002\u7576\u6975\u9577\u93c8\u8102\u80aa\u9178\u6fc3\u5ea6\u9ad8\u65bc\u6b63\u5e38\u503c\uff0c\u800c\u63a5\u7372\u63a1\u96c6\u9662\u6240\u901a\u77e5\u6642\uff0c\u8acb\u5118\u901f\u914d\u5408\u91ab\u7642\u4eba\u54e1\u6307\u793a\u9032\u884c\u8907\u6aa2\u3002\u82e5\u65b0\u751f\u5152\u6709\u76f8\u95dc\u81e8\u5e8a\u75c7\u72c0\u6642\uff0c\u8acb\u7acb\u5373\u8207\u65b0\u751f\u5152\u7be9\u6aa2\u4e2d\u5fc3\u6216\u7576\u5730\u6240\u5c6c\u8f49\u4ecb\u91ab\u9662\u91ab\u5e2b\u806f\u7d61\uff0c\u5c0b\u6c42\u53ca\u6642\u7684\u91ab\u7642\u5354\u52a9\u3002<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\"><strong>\u6975\u9577\u93c8\u91af\u8f14\u9176<\/strong><strong>A<\/strong><strong>\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7<\/strong><strong>\u78ba\u8a3a\u8a55\u4f30\u65b9\u5f0f<\/strong><\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li>\u81e8\u5e8a\u75c7\u72c0\u8a55\u4f30<\/li>\n<li>\u6025\u6027\u767c\u75c5\u6642\u7684\u8840\u6f3f\u6216\u662f\u8840\u7247\u91af\u57fa\u8089\u9e7c\u5206\u6790<\/li>\n<li><em>ACADVL<\/em>\u57fa\u56e0\u7a81\u8b8a\u5206\u6790<\/li>\n<li>\u57f9\u990a\u7e96\u7dad\u6bcd\u7d30\u80de\u6216\u6dcb\u5df4\u7403\u7684VLCAD\u9175\u7d20\u6d3b\u6027\u5206\u6790<\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\"><strong>\u6975\u9577\u93c8\u91af\u8f14\u9176<\/strong><strong>A<\/strong><strong>\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7<\/strong><strong>\u6cbb\u7642\u65b9\u5f0f<\/strong><\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li>\u98f2\u98df\u65b9\u9762\u53ef\u7d66\u4e88\u4f4e\u8102\u80aa\uff0c\u4e26\u5229\u7528\u4e2d\u93c8\u8102\u80aa\u9178\u4ee5\u589e\u52a0\u71b1\u91cf\uff0c\u4f46\u8981\u907f\u514d\u98e2\u9913\u53ca\u7981\u98df\u7684\u60c5\u5f62\u767c\u751f\u3002<\/li>\n<li>\u6025\u6027\u767c\u4f5c\u6642\u61c9\u4f7f\u7528\u975c\u8108\u6ce8\u5c04\u542b\u7cd6\u9ede\u6ef4\u4f5c\u70ba\u80fd\u91cf\u4f86\u6e90\u3001\u6cbb\u7642\u5fc3\u5f8b\u554f\u984c\u3001\u76e3\u6e2c\u6a6b\u7d0b\u808c\u6eb6\u89e3\u75c7\u3002<\/li>\n<li>\u5fc3\u81df\u529f\u80fd\u7570\u5e38\u53ef\u900f\u904e\u65e9\u671f\u7a4d\u6975\u652f\u6301\u6027\u7642\u6cd5\u53ca\u98f2\u98df\u63a7\u5236\u4f86\u6539\u5584\uff0c\u5fc3\u8870\u7aed\u60a3\u8005\u7d66\u4e88\u5fc3\u808c\u652f\u6301\u7642\u6cd5\u3002<\/li>\n<li>\u6025\u6027\u6a6b\u7d0b\u808c\u6eb6\u89e3\u75c7\u53ef\u900f\u904e\u5927\u91cf\u88dc\u5145\u6c34\u5206\u53ca\u9e7c\u5316\u5c3f\u6db2\u4f86\u4fdd\u8b77\u814e\u529f\u80fd\u4e26\u9810\u9632\u6025\u6027\u814e\u8870\u7aed\u3002<\/li>\n<li>\u5728\u75be\u75c5\u8ffd\u8e64\u65b9\u9762\uff0c\u61c9\u5b9a\u671f\u76e3\u6e2c\u4e32\u806f\u8cea\u8b5c\u5100\u5206\u6790\u3001\u98f2\u98df\u72c0\u614b\uff0c\u808c\u8089\u9175\u7d20\u3001\u5fc3\u81df\u72c0\u614b\u3001\u751f\u9577\u53ca\u767c\u5c55\u72c0\u614b<\/li>\n<\/ul>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul style=\"list-style-type: square;\">\n<li style=\"text-align: justify;\">\u5c0d\u65bc\u56b4\u91cd\u65e9\u767c\u578b\u75c5\u60a3\uff0c\u5fc3\u808c\u75c5\u8b8a\u548c\u5fc3\u5f8b\u4e0d\u6574\u662f\u53ef\u80fd\u662f\u81f4\u547d\u3002\u7136\u800c\uff0c\u901a\u904e\u65e9\u671f\u6cbb\u7642\u548c\u7279\u5b9a\u98f2\u98df\u6539\u8b8a\u53ef\u4ee5\u6539\u5584\u5fc3\u81df\u529f\u80fd\u3002<\/li>\n<li style=\"text-align: justify;\">\u5c0d\u65bc\u809d\u81df\u578b\/\u4f4e\u916e\u9ad4\u6027\u4f4e\u8840\u7cd6\u578b\uff0c\u61c9\u907f\u514d\u4f4e\u916e\u75c7\u4f4e\u8840\u7cd6\u5c0e\u81f4\u5931\u53bb\u610f\u8b58\u6216\u7672\u7647\u767c\u4f5c\u3002<\/li>\n<li style=\"text-align: justify;\">\u665a\u767c\u6027\u808c\u8089\u75c5\u8b8a\u578b\u5f62\u5f0f\u7684\u4eba\u53ef\u80fd\u53ea\u6709\u808c\u8089\u76f8\u95dc\u7684\u75c7\u72c0\u3002\u6709\u4e9b\u4eba\u53ef\u80fd\u56e0\u75c7\u72c0\u8f15\u5fae\u6216\u9593\u6b47\u6027\u767c\u751f\u800c\u5728\u5176\u4e00\u751f\u4e2d\u6c92\u6709\u767c\u89ba\u4efb\u4f55\u75c7\u72c0\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3><strong><span style=\"font-size: 14pt;\">\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7<\/span>\u7684\u7be9\u6aa2\u65b9\u6cd5<\/strong><\/h3>\n<ul>\n<li style=\"text-align: justify;\">\u7b2c\u4e00\u7dda\u6aa2\u9a57\n<ul style=\"list-style-type: square;\">\n<li>\u6aa2\u9a57\u65b9\u5f0f\uff1a\u751f\u5316\u6aa2\u9a57\uff0c\u4f7f\u7528\u542b\u7a69\u5b9a\u540c\u4f4d\u7d20\u6a19\u8a18\u7684\u5167\u90e8\u6a19\u6e96\u54c1\uff08Internal Standard\uff09\u6eb6\u5291\u8403\u53d6\u4e7e\u71e5\u8840\u9ede\u4e2d\u7684\u8102\u80aa\u9178\uff0c\u518d\u4ee5\u4e32\u806f\u8cea\u8b5c\u5100\uff08MS\/MS\uff09\u9032\u884c\u5206\u6790\u3002\uff08111.3-\u81f3\u4eca\uff09<\/li>\n<li>\u6aa2\u9a57\u8a66\u5291\uff1aNeoBase<sup>TM<\/sup>\u00a02 Non-derivatized MSMS kit\uff08PerkinElmer\uff09<\/li>\n<\/ul>\n<\/li>\n<li>\u7b2c\u4e8c\u7dda\u6aa2\u9a57\n<ul style=\"list-style-type: square;\">\n<li style=\"text-align: justify;\">\u6aa2\u9a57\u65b9\u5f0f\uff1a\u57fa\u56e0\u6aa2\u6e2c\uff0c\u6b21\u4e16\u4ee3\u5b9a\u5e8f\uff08Next Generation Sequencing\uff0cNGS\uff09\u3002\uff08108.10-\u81f3\u4eca\uff09<\/li>\n<li style=\"text-align: justify;\">\u6aa2\u9a57\u8a66\u5291\uff1aFatty Acids 7-Gene Lib Prep Kit\uff08Qiagen\uff09<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u4ec0\u9ebc\u662f\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7\uff1f \u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7\u60a3\u8005\u8eab\u9ad4\u7f3a\u4e4f\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7121\u6cd5\u5c07\u67d0\u4e9b &#8230; <a title=\"\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7 (VLCAD)\" class=\"read-more\" href=\"https:\/\/www.cfoh.org.tw\/index.php\/item\/vlcadd\/\" aria-label=\"\u95b1\u8b80\u3008\u6975\u9577\u93c8\u91af\u8f14\u9176A\u812b\u6c2b\u9175\u7d20\u7f3a\u4e4f\u75c7 (VLCAD)\u3009\u5168\u6587\">\u95b1\u8b80\u5168\u6587<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"parent":781,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P9uzrk-9l","_links":{"self":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/579"}],"collection":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/comments?post=579"}],"version-history":[{"count":5,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/579\/revisions"}],"predecessor-version":[{"id":2635,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/579\/revisions\/2635"}],"up":[{"embeddable":true,"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/pages\/781"}],"wp:attachment":[{"href":"https:\/\/www.cfoh.org.tw\/index.php\/wp-json\/wp\/v2\/media?parent=579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}